Skip to main content

The cutting edge of bone

Advancing monoclonal antibodies, multi-specifics and ADCs engineered to have enhanced efficacy in the skeleton

Capabilities

Platform capabilities

Bone is not just inert scaffold - it is an active driver of many disease states. We have built a first-in-class antibody engineering platform to enhance the performance of antibodies in bone.

1

Disease, target and modality identification

Tailored engineering approaches optimized for solid tumors, liquid tumors, osteoporosis, arthritis, and rare skeletal dysplasias across monoclonal antibodies, multi-specifics, or antibody-drug conjugates.

2

Antibody re-engineering

Apply proprietary datasets, AI/ML approaches and proprietary experimental systems to enhance bone performance while also achieving excellent developability.

3

Selectively enhanced efficacy in the skeleton

Production of a bone enhanced drug with exceptional developability and safety.