The cutting edge of bone
Advancing monoclonal antibodies, multi-specifics and ADCs engineered to have enhanced efficacy in the skeleton
Platform capabilities
Bone is not just inert scaffold - it is an active driver of many disease states. We have built a first-in-class antibody engineering platform to enhance the performance of antibodies in bone.
Disease, target and modality identification
Tailored engineering approaches optimized for solid tumors, liquid tumors, osteoporosis, arthritis, and rare skeletal dysplasias across monoclonal antibodies, multi-specifics, or antibody-drug conjugates.
Antibody re-engineering
Apply proprietary datasets, AI/ML approaches and proprietary experimental systems to enhance bone performance while also achieving excellent developability.
Selectively enhanced efficacy in the skeleton
Production of a bone enhanced drug with exceptional developability and safety.





















